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Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants.

A gene in chromosome region 13q14 has been identified as the human retinoblastoma susceptibility (RB) gene on the basis of altered gene expression found in virtually all retinoblastomas. In order to further characterize the RB gene and its structural alterations, we examined genomic clones of the RB...

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Autors principals: Bookstein, R, Lee, E Y, To, H, Young, L J, Sery, T W, Hayes, R C, Friedmann, T, Lee, W H
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC279959/
https://ncbi.nlm.nih.gov/pubmed/2895471
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