Generation of Functional Human Hepatic Endoderm from Human iPS cells

With the advent of induced pluripotent stem cell (iPSC) technology, it is now feasible to generate iPSCs with a defined genotype or disease state. When coupled with direct differentiation of defined lineage, such as hepatic endoderm (HE). iPSC would revolutionise the way we study human liver biology...

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Main Authors: Sullivan, Gareth J., Hay, David C., Park, In-Hyun, Fletcher, Judy, Hannoun, Zara, Payne, Catherine M., Dalgetty, Donna, Black, James R., Ross, James A., Samuel, Kay, Wang, Gang, Daley, George Q., Lee, Je-Hyuk, Church, George M., Forbes, Stuart J., Iredale, John P., Wilmut, Ian
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799548/
https://ncbi.nlm.nih.gov/pubmed/19877180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23335
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