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A New Target for Amyloid Beta Toxicity Validated by Standard and High-Throughput Electrophysiology

BACKGROUND: Soluble oligomers of amyloid beta (Aβ) are considered to be one of the major contributing factors to the development of Alzheimer's disease. Most therapeutic development studies have focused on toxicity directly at the synapse. METHODOLOGY/PRINCIPAL FINDINGS: Patch clamp studies det...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Varghese, Kucku, Molnar, Peter, Das, Mainak, Bhargava, Neelima, Lambert, Stephen, Kindy, Mark S., Hickman, James J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799531/
https://ncbi.nlm.nih.gov/pubmed/20062810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008643
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