Benzo[alpha]pyrene diol epoxide I binds to DNA at replication forks.

The distribution of lesions in DNA caused by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo [alpha]pyrene (B[alpha]P diol epoxide-I) was studied in synchronized C3H/10T1/2 cells treated in S phase. Sites of carcinogen modification of DNA were identified by polyclonal...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Paules, R S, Cordeiro-Stone, M, Mass, M J, Poirier, M C, Yuspa, S H, Kaufman, D G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3127827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2176
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