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Activation of the protein-tyrosine kinase associated with the bombesin receptor complex in small cell lung carcinomas.

It has been hypothesized that bombesin-like peptides produced by small cell lung carcinomas may sustain deregulated proliferation through an autocrine mechanism. We have shown that the neuropeptide bombesin leads to the activation of a protein-tyrosine kinase that phosphorylates a 115-kDa protein (p...

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Autori principali: Gaudino, G, Cirillo, D, Naldini, L, Rossino, P, Comoglio, P M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC279950/
https://ncbi.nlm.nih.gov/pubmed/2451242
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