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Activation of the protein-tyrosine kinase associated with the bombesin receptor complex in small cell lung carcinomas.

It has been hypothesized that bombesin-like peptides produced by small cell lung carcinomas may sustain deregulated proliferation through an autocrine mechanism. We have shown that the neuropeptide bombesin leads to the activation of a protein-tyrosine kinase that phosphorylates a 115-kDa protein (p...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gaudino, G, Cirillo, D, Naldini, L, Rossino, P, Comoglio, P M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279950/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2451242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2166
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