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Identifying quantitative operation principles in metabolic pathways: a systematic method for searching feasible enzyme activity patterns leading to cellular adaptive responses

BACKGROUND: Optimization methods allow designing changes in a system so that specific goals are attained. These techniques are fundamental for metabolic engineering. However, they are not directly applicable for investigating the evolution of metabolic adaptation to environmental changes. Although b...

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Main Authors: Guillén-Gosálbez, Gonzalo, Sorribas, Albert
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799421/
https://ncbi.nlm.nih.gov/pubmed/19930714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-386
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