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Geometry of the simian virus 40 large tumor antigen-DNA complex as probed by protease digestion.

I have mapped the regions of simian virus 40 (SV40)-encoded large tumor (T) antigen that remained associated with origin-containing SV40 DNA after digestion with various concentrations of Pronase E, a nonspecific protease. Immunoaffinity-purified, labeled T antigen was bound to SV40 DNA-cellulose an...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Author: Simmons, D T
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2832846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.7.2086
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