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CCR7 Deficiency Exacerbates Injury in Acute Nephritis Due to Aberrant Localization of Regulatory T Cells

The homing of dendritic cells and T cells to secondary lymphoid organs requires chemokine receptor 7 (CCR7) expression on these cells. T cells mediate the pathogenesis of experimental accelerated nephrotoxic serum nephritis (NTS), including its suppression by regulatory T cells (Tregs), but the cont...

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Detalles Bibliográficos
Main Authors: Eller, Kathrin, Weber, Tobias, Pruenster, Monika, Wolf, Anna M., Mayer, Gert, Rosenkranz, Alexander R., Rot, Antal
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799279/
https://ncbi.nlm.nih.gov/pubmed/19917782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009020133
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