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The retinoblastoma tumor suppressor gene, the exception that proves the rule
The retinoblastoma tumor suppressor gene (Rb1) is centrally important in cancer research. Mutational inactivation of Rb1 causes the pediatric cancer retinoblastoma, while deregulation of the pathway in which it functions is common in most types of human cancer. The Rb1 encoded protein (pRb) is well...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799241/ https://ncbi.nlm.nih.gov/pubmed/16936742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209616 |
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