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BTLA mediates inhibition of human tumor-specific CD8(+) T cells that can be partially reversed by vaccination
The function of antigen-specific CD8(+) T cells, which may protect against both infectious and malignant diseases, can be impaired by ligation of their inhibitory receptors, which include CTL-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1). Recently, B and T lymphocyte attenuator (B...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799219/ https://ncbi.nlm.nih.gov/pubmed/20038811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40070 |
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