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BTLA mediates inhibition of human tumor-specific CD8(+) T cells that can be partially reversed by vaccination

The function of antigen-specific CD8(+) T cells, which may protect against both infectious and malignant diseases, can be impaired by ligation of their inhibitory receptors, which include CTL-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1). Recently, B and T lymphocyte attenuator (B...

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Main Authors: Derré, Laurent, Rivals, Jean-Paul, Jandus, Camilla, Pastor, Sonia, Rimoldi, Donata, Romero, Pedro, Michielin, Olivier, Olive, Daniel, Speiser, Daniel E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799219/
https://ncbi.nlm.nih.gov/pubmed/20038811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40070
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