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The cytolytic C5b-9 complement complex: feedback inhibition of complement activation.
We describe a regulatory function of the terminal cytolytic C5b-9 complex [C5b-9(m)] of human complement. Purified C5b-9(m) complexes isolated from target membranes, whether in solution or bound to liposomes, inhibited lysis of sensitized sheep erythrocytes by whole human serum in a dose-dependent m...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3162317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.6.1912 |
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