The cytolytic C5b-9 complement complex: feedback inhibition of complement activation.

We describe a regulatory function of the terminal cytolytic C5b-9 complex [C5b-9(m)] of human complement. Purified C5b-9(m) complexes isolated from target membranes, whether in solution or bound to liposomes, inhibited lysis of sensitized sheep erythrocytes by whole human serum in a dose-dependent m...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Bhakdi, S, Maillet, F, Muhly, M, Kazatchkine, M D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3162317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.6.1912
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