PIB Imaging Predicts Progression from Cognitively Normal to Symptomatic Alzheimer’s Disease

OBJECTIVE: To determine whether preclinical Alzheimer’s disease (AD), as detected by the amyloid imaging agent Pittsburgh Compound B (PIB) in cognitively normal older adults, is associated with risk of symptomatic AD. DESIGN: A longitudinal cohort study of cognitively normal older adults assessed wi...

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Main Authors: Morris, John C., Roe, Catherine M., Grant, Elizabeth A., Head, Denise, Storandt, Martha, Goate, Alison M., Fagan, Anne M., Holtzman, David M., Mintun, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798814/
https://ncbi.nlm.nih.gov/pubmed/20008650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.269
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