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Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

The physiological role of fungal galectins has remained elusive. Here, we show that feeding of a mushroom galectin, Coprinopsis cinerea CGL2, to Caenorhabditis elegans inhibited development and reproduction and ultimately resulted in killing of this nematode. The lack of toxicity of a carbohydrate-b...

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Detalhes bibliográficos
Main Authors: Butschi, Alex, Titz, Alexander, Wälti, Martin A., Olieric, Vincent, Paschinger, Katharina, Nöbauer, Katharina, Guo, Xiaoqiang, Seeberger, Peter H., Wilson, Iain B. H., Aebi, Markus, Hengartner, Michael O., Künzler, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798750/
https://ncbi.nlm.nih.gov/pubmed/20062796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000717
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