Molecular Basis for Galactosylation of Core Fucose Residues in Invertebrates: IDENTIFICATION OF CAENORHABDITIS ELEGANS N-GLYCAN CORE α1,6-FUCOSIDE β1,4-GALACTOSYLTRANSFERASE GALT-1 AS A MEMBER OF A NOVEL GLYCOSYLTRANSFERASE FAMILY

Galectin CGL2 from the ink cap mushroom Coprinopsis cinerea displays toxicity toward the model nematode Caenorhabditis elegans. A mutation in a putative glycosyltransferase-encoding gene resulted in a CGL2-resistant C. elegans strain characterized by N-glycans lacking the β1,4-galactoside linked to...

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Detalhes bibliográficos
Main Authors: Titz, Alexander, Butschi, Alex, Henrissat, Bernard, Fan, Yao-Yun, Hennet, Thierry, Razzazi-Fazeli, Ebrahim, Hengartner, Michael O., Wilson, Iain B. H., Künzler, Markus, Aebi, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794738/
https://ncbi.nlm.nih.gov/pubmed/19858195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.058354
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