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Oxidant stress derails the cardiac connexon connection

Connexin 43 (Cx43) is the major protein component of gap junctions that electrically couple cardiomyocytes at the intercalated disc. Oxidant stress, reduced Cx43 expression, and altered subcellular localization are present in many forms of structural heart disease. These changes in Cx43 lead to alte...

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Bibliografske podrobnosti
Glavni avtor: Tomaselli, Gordon F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798705/
https://ncbi.nlm.nih.gov/pubmed/20038808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41780
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