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Oxidant stress derails the cardiac connexon connection

Connexin 43 (Cx43) is the major protein component of gap junctions that electrically couple cardiomyocytes at the intercalated disc. Oxidant stress, reduced Cx43 expression, and altered subcellular localization are present in many forms of structural heart disease. These changes in Cx43 lead to alte...

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Bibliografiska uppgifter
Huvudupphovsman: Tomaselli, Gordon F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798705/
https://ncbi.nlm.nih.gov/pubmed/20038808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41780
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