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Oxidant stress derails the cardiac connexon connection
Connexin 43 (Cx43) is the major protein component of gap junctions that electrically couple cardiomyocytes at the intercalated disc. Oxidant stress, reduced Cx43 expression, and altered subcellular localization are present in many forms of structural heart disease. These changes in Cx43 lead to alte...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798705/ https://ncbi.nlm.nih.gov/pubmed/20038808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41780 |
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