CD20 deficiency in humans results in impaired T cell–independent antibody responses

CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD20 in human B cell physiology has remained elusive. We describe here a juvenile pa...

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Main Authors: Kuijpers, Taco W., Bende, Richard J., Baars, Paul A., Grummels, Annette, Derks, Ingrid A.M., Dolman, Koert M., Beaumont, Tim, Tedder, Thomas F., van Noesel, Carel J.M., Eldering, Eric, van Lier, René A.W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798692/
https://ncbi.nlm.nih.gov/pubmed/20038800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40231
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