CD20 deficiency in humans results in impaired T cell–independent antibody responses

CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD20 in human B cell physiology has remained elusive. We describe here a juvenile pa...

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Autors principals: Kuijpers, Taco W., Bende, Richard J., Baars, Paul A., Grummels, Annette, Derks, Ingrid A.M., Dolman, Koert M., Beaumont, Tim, Tedder, Thomas F., van Noesel, Carel J.M., Eldering, Eric, van Lier, René A.W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798692/
https://ncbi.nlm.nih.gov/pubmed/20038800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40231
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