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Germinal centers in human lymph nodes contain reactivated memory B cells
To reveal migration trails of antigen-responsive B cells in lymphoid tissue, we analyzed immunoglobulin (Ig)M-V(H) and IgG-V(H) transcripts of germinal center (GC) samples microdissected from three reactive human lymph nodes. Single B cell clones were found in multiple GCs, one clone even in as many...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118493/ https://ncbi.nlm.nih.gov/pubmed/17938234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071006 |
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