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Dysregulated sarcoplasmic reticulum calcium release: Potential pharmacological target in cardiac disease
In the heart, Ca(2+) released from the intracellular Ca(2+) storage site, the sarcoplasmic reticulum (SR), is the principal determinant of cardiac contractility. SR Ca(2+) release is controlled by dedicated molecular machinery, composed of the cardiac ryanodine receptor (RyR2) and a number of access...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798594/ https://ncbi.nlm.nih.gov/pubmed/18675300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2008.06.002 |
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