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Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease

HIV-1 protease processes the Gag and Gag-Pol polyproteins into mature structural and functional proteins, including itself, and is therefore indispensable for viral maturation1,2. The mature protease is active only as a dimer3–5 with each subunit contributing catalytic residues6. The full-length tra...

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Detalles Bibliográficos
Main Authors: Tang, Chun, Louis, John M., Aniana, Annie, Suh, Jeong-Yong, Clore, G. Marius
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798589/
https://ncbi.nlm.nih.gov/pubmed/18833280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07342
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