Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

Favipiravir (T-705 [6-fluoro-3-hydroxy-2-pyrazinecarboxamide]) and oseltamivir were combined to treat influenza virus A/NWS/33 (H1N1), A/Victoria/3/75 (H3N2), and A/Duck/MN/1525/81 (H5N1) infections. T-705 alone inhibited viruses in cell culture at 1.4 to 4.3 μM. Oseltamivir inhibited these three vi...

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Autori principali: Smee, Donald F., Hurst, Brett L., Wong, Min-Hui, Bailey, Kevin W., Tarbet, E. Bart, Morrey, John D., Furuta, Yousuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798555/
https://ncbi.nlm.nih.gov/pubmed/19901093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00933-09
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