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Absorption, Pharmacokinetics, and Safety of Triclosan after Dermal Administration

We evaluated the pharmacokinetics and safety of the antimicrobial agent triclosan after dermal application of a 2% triclosan-containing cream to six volunteers. Percutaneous absorption calculated from urinary excretion was 5.9% ± 2.1% of the dose (mean ± standard deviation). The amount absorbed sugg...

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Detalhes bibliográficos
Main Authors: Queckenberg, Christian, Meins, Jürgen, Wachall, Bertil, Doroshyenko, Oxana, Tomalik-Scharte, Dorota, Bastian, Bärbel, Abdel-Tawab, Mona, Fuhr, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798550/
https://ncbi.nlm.nih.gov/pubmed/19822703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00615-09
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