Molecular Correlates of High-Level Antifolate Resistance in Rwandan Children with Plasmodium falciparum Malaria

Antifolate drugs have an important role in the treatment of malaria. Polymorphisms in the genes encoding the dihydrofolate reductase and dihydropteroate synthetase enzymes cause resistance to the antifol and sulfa drugs, respectively. Rwanda has the highest levels of antimalarial drug resistance in...

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Detaylı Bibliyografya
Asıl Yazarlar: Karema, Corine, Imwong, Mallika, Fanello, Caterina I., Stepniewska, Kasia, Uwimana, Aline, Nakeesathit, Supatchara, Dondorp, Arjen, Day, Nicholas P., White, Nicholas J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798539/
https://ncbi.nlm.nih.gov/pubmed/19841150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00498-09
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