Method for Screening Compounds That Influence Virulence Gene Expression in Staphylococcus aureus

We present a simple assay to examine effects of compounds on virulence gene expression in the human pathogen Staphylococcus aureus. The assay employs transcriptional reporter strains carrying lacZ fused to central virulence genes. Compounds affecting virulence gene expression and activity of the agr...

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Bibliographic Details
Main Authors: Nielsen, Anita, Nielsen, Kristian F., Frees, Dorte, Larsen, Thomas O., Ingmer, Hanne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Analytical Procedures
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798519/
https://ncbi.nlm.nih.gov/pubmed/19917763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00940-09
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