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Method for Screening Compounds That Influence Virulence Gene Expression in Staphylococcus aureus

We present a simple assay to examine effects of compounds on virulence gene expression in the human pathogen Staphylococcus aureus. The assay employs transcriptional reporter strains carrying lacZ fused to central virulence genes. Compounds affecting virulence gene expression and activity of the agr...

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Detalhes bibliográficos
Main Authors: Nielsen, Anita, Nielsen, Kristian F., Frees, Dorte, Larsen, Thomas O., Ingmer, Hanne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798519/
https://ncbi.nlm.nih.gov/pubmed/19917763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00940-09
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