Loading...

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in broth culture or within human macrophages can acquire Fe from the two major host Fe-binding proteins, lactoferrin (Lf) and transferrin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Olakanmi, Oyebode, Gunn, John S., Su, Shengchang, Soni, Shilpa, Hassett, Daniel J., Britigan, Bradley E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798485/
https://ncbi.nlm.nih.gov/pubmed/19917753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00655-09
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!