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Different Tempo and Anatomic Location of Dual-Tropic and X4 Virus Emergence in a Model of R5 Simian-Human Immunodeficiency Virus Infection

We previously reported coreceptor switch in rhesus macaques inoculated intravenously with R5 simian-human immunodeficiency virus SF162P3N (SHIV(SF162P3N)). Whether R5-to-X4 virus evolution occurs in mucosally infected animals and in which anatomic site the switch occurs, however, were not addressed....

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Détails bibliographiques
Auteurs principaux: Ren, Wuze, Tasca, Silvana, Zhuang, Ke, Gettie, Agegnehu, Blanchard, James, Cheng-Mayer, Cecilia
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798429/
https://ncbi.nlm.nih.gov/pubmed/19846515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01865-09
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