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The Effects of Influenza A Virus PB1-F2 Protein on Polymerase Activity Are Strain Specific and Do Not Impact Pathogenesis

The influenza A virus PB1-F2 protein has been implicated as a virulence factor, but the mechanism by which it enhances pathogenicity is not understood. The PB1 gene segment of the H1N1 swine-origin influenza virus pandemic strain codes for a truncated PB1-F2 protein which terminates after 11 amino a...

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Autori principali: McAuley, Julie L., Zhang, Kelly, McCullers, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798424/
https://ncbi.nlm.nih.gov/pubmed/19828614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01785-09
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