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Targeting of Murine Leukemia Virus Gag to the Plasma Membrane Is Mediated by PI(4,5)P(2)/PS and a Polybasic Region in the Matrix

Membrane targeting of the human immunodeficiency virus Gag proteins is dependent on phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)] located in the plasma membrane. In order to determine if evolutionarily distant retroviral Gag proteins are targeted by a similar mechanism, we generated mutants...

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Detalhes bibliográficos
Main Authors: Hamard-Peron, E., Juillard, F., Saad, J. S., Roy, C., Roingeard, P., Summers, M. F., Darlix, J.-L., Picart, C., Muriaux, D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798412/
https://ncbi.nlm.nih.gov/pubmed/19828619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01134-09
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