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A trans-Complementing Recombination Trap Demonstrates a Low Propensity of Flaviviruses for Intermolecular Recombination

Intermolecular recombination between the genomes of closely related RNA viruses can result in the emergence of novel strains with altered pathogenic potential and antigenicity. Although recombination between flavivirus genomes has never been demonstrated experimentally, the potential risk of generat...

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Bibliographic Details
Main Authors: Taucher, Christian, Berger, Angelika, Mandl, Christian W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798405/
https://ncbi.nlm.nih.gov/pubmed/19864381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01063-09
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