Functional Analysis of the Tick-Borne Encephalitis Virus Cyclization Elements Indicates Major Differences between Mosquito-Borne and Tick-Borne Flaviviruses

The linear, positive-stranded RNA genome of flaviviruses is thought to adopt a circularized conformation via interactions of short complementary sequence elements located within its terminal regions. This process of RNA cyclization is a crucial precondition for RNA replication. In the case of mosqui...

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Detalhes bibliográficos
Main Authors: Kofler, Regina M., Hoenninger, Verena M., Thurner, Caroline, Mandl, Christian W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440478/
https://ncbi.nlm.nih.gov/pubmed/16571826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.4099-4113.2006
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