Anti-Glycoprotein H Antibody Impairs the Pathogenicity of Varicella-Zoster Virus in Skin Xenografts in the SCID Mouse Model

Varicella-zoster virus (VZV) infection is usually mild in healthy individuals but can cause severe disease in immunocompromised patients. Prophylaxis with varicella-zoster immunoglobulin can reduce the severity of VZV if given shortly after exposure. Glycoprotein H (gH) is a highly conserved herpesv...

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Main Authors: Vleck, Susan E., Oliver, Stefan L., Reichelt, Mike, Rajamani, Jaya, Zerboni, Leigh, Jones, Carol, Zehnder, James, Grose, Charles, Arvin, Ann M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798403/
https://ncbi.nlm.nih.gov/pubmed/19828615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01338-09
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