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The Human Papillomavirus Type 18 E2 Protein Is a Cell Cycle-Dependent Target of the SCF(Skp2) Ubiquitin Ligase

The human papillomavirus type 18 (HPV-18) E2 gene is inactivated in cervical carcinoma after integration of the viral DNA into the host cellular genome. Since E2 represses the transcription of the two viral oncogenes E6 and E7, integration which allows their strong expression is considered a major s...

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Bibliografiske detaljer
Main Authors: Bellanger, Sophie, Tan, Chye Ling, Nei, Wenlong, He, Ping Ping, Thierry, Françoise
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798402/
https://ncbi.nlm.nih.gov/pubmed/19828607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01162-09
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