A U(L)47 Gene Deletion Mutant of Bovine Herpesvirus Type 1 Exhibits Impaired Growth in Cell Culture and Lack of Virulence in Cattle

Tegument protein VP8 encoded by the U(L)47 gene of bovine herpesvirus type 1 (BHV-1) is the most abundant constituent of mature virions. In the present report, we describe the characterization of U(L)47 gene-deleted BHV-1 in cultured cells and its natural host. The U(L)47 deletion mutant exhibited r...

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Hauptverfasser: Lobanov, Vladislav A., Maher-Sturgess, Sheryl L., Snider, Marlene G., Lawman, Zoe, Babiuk, Lorne A., van Drunen Littel-van den Hurk, Sylvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798391/
https://ncbi.nlm.nih.gov/pubmed/19864376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01544-09
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