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Phosphorylation of Bovine Herpesvirus 1 VP8 Plays a Role in Viral DNA Encapsidation and Is Essential for Its Cytoplasmic Localization and Optimal Virion Incorporation

VP8 is a major tegument protein of bovine herpesvirus 1 (BoHV-1) and is essential for viral replication in cattle. The protein undergoes phosphorylation after transcription through cellular casein kinase 2 (CK2) and a viral kinase, US3. In this study, a virus containing a mutated VP8 protein that is...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Zhang, Kuan, Brownlie, Robert, Snider, Marlene, van Drunen Littel-van den Hurk, Sylvia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836321/
https://ncbi.nlm.nih.gov/pubmed/26889039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00219-16
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