Herpes Simplex Virus Type 1 (HSV-1)-Induced Apoptosis in Human Dendritic Cells as a Result of Downregulation of Cellular FLICE-Inhibitory Protein and Reduced Expression of HSV-1 Antiapoptotic Latency-Associated Transcript Sequences

Herpes simplex virus type 1 (HSV-1) is one of the most frequent and successful human pathogens. It targets immature dendritic cells (iDCs) to interfere with the antiviral immune response. The mechanisms underlying apoptosis of HSV-1-infected iDCs are not fully understood. Previously, we have shown t...

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Main Authors: Kather, Angela, Raftery, Martin J., Devi-Rao, Gayathri, Lippmann, Juliane, Giese, Thomas, Sandri-Goldin, Rozanne M., Schönrich, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798353/
https://ncbi.nlm.nih.gov/pubmed/19906927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01409-09
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