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Late Domain-Independent Rescue of a Release-Deficient Moloney Murine Leukemia Virus by the Ubiquitin Ligase Itch

Moloney murine leukemia virus (MoMLV) Gag utilizes its late (L) domain motif PPPY to bind members of the Nedd4-like ubiquitin ligase family. These interactions recruit components of the cell's budding machinery that are critical for virus release. MoMLV Gag contains two additional L domains, PS...

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Detalhes bibliográficos
Main Authors: Jadwin, Joshua A., Rudd, Victoria, Sette, Paola, Challa, Swathi, Bouamr, Fadila
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798346/
https://ncbi.nlm.nih.gov/pubmed/19864377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01319-09
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