Vaccination To Induce Antibodies Blocking the CX3C-CX3CR1 Interaction of Respiratory Syncytial Virus G Protein Reduces Pulmonary Inflammation and Virus Replication in Mice

Respiratory syncytial virus (RSV) infection causes substantial morbidity and some deaths in the young and elderly worldwide. There is no safe and effective vaccine available, although it is possible to reduce the hospitalization rate for high-risk children by anti-RSV antibody prophylaxis. RSV has b...

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Bibliografiske detaljer
Main Authors: Zhang, Wenliang, Choi, Youngjoo, Haynes, Lia M., Harcourt, Jennifer L., Anderson, Larry J., Jones, Les P., Tripp, Ralph A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798341/
https://ncbi.nlm.nih.gov/pubmed/19864390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01755-09
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