Respiratory Syncytial Virus (RSV) G Protein Vaccines With Central Conserved Domain Mutations Induce CX3C-CX3CR1 Blocking Antibodies

Respiratory syncytial virus (RSV) infection can cause bronchiolitis, pneumonia, morbidity, and some mortality, primarily in infants and the elderly, for which no vaccine is available. The RSV attachment (G) protein contains a central conserved domain (CCD) with a CX3C motif implicated in the inducti...

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發表在:Viruses
Main Authors: Bergeron, Harrison C., Murray, Jackelyn, Nuñez Castrejon, Ana M., DuBois, Rebecca M., Tripp, Ralph A.
格式: Artigo
語言:Inglês
出版: MDPI 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926521/
https://ncbi.nlm.nih.gov/pubmed/33672319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020352
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