Regulation of G-Protein Signaling by RKTG via Sequestration of the Gβγ Subunit to the Golgi Apparatus

Upon ligand binding, G-protein-coupled receptors (GPCRs) impart the signal to heterotrimeric G proteins composed of α, β, and γ subunits, leading to dissociation of the Gα subunit from the Gβγ subunit. While the Gα subunit is imperative for downstream signaling, the Gβγ subunit, in its own right, me...

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Hlavní autoři: Jiang, Yuhui, Xie, Xiaoduo, Zhang, Yixuan, Luo, Xiaolin, Wang, Xiao, Fan, Fengjuan, Zheng, Dawei, Wang, Zhenzhen, Chen, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798304/
https://ncbi.nlm.nih.gov/pubmed/19884349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01038-09
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