Fluorescence Resonance Energy Transfer Analysis of Merlin Conformational Changes

Neurofibromatosis type 2 is an inherited autosomal disorder caused by biallelic inactivation of the NF2 tumor suppressor gene. The NF2 gene encodes a 70-kDa protein, merlin, which is a member of the ezrin-radixin-moesin (ERM) family. ERM proteins are believed to be regulated by a transition between...

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Bibliographic Details
Main Authors: Hennigan, Robert F., Foster, Lauren A., Chaiken, Mary F., Mani, Timmy, Gomes, Michelle M., Herr, Andrew B., Ip, Wallace
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798298/
https://ncbi.nlm.nih.gov/pubmed/19884346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00248-09
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