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Highly potent antagonists of luteinizing hormone-releasing hormone free of edematogenic effects.

To eliminate the undesirable edematogenic effect of the luteinizing hormone-releasing hormone (LH-RH) antagonists containing basic D amino acids at position 6, exemplified by [Ac-D-Phe(pCl)1,2,D-Trp3,D-Arg6,D-Ala10]LH-RH [Phe(pCl) indicates 4-chlorophenylalanine], analogs with D-ureidoalkyl amino ac...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Bajusz, S, Kovacs, M, Gazdag, M, Bokser, L, Karashima, T, Csernus, V J, Janaky, T, Guoth, J, Schally, A V
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3278323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1637
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