Retroviral transfer of a murine cDNA for multidrug resistance confers pleiotropic drug resistance to cells without prior drug selection.
We have constructed a retrovirus expression vector that carries the murine mdr cDNA transcribed under the control of the human H4 histone promoter to examine the feasibility of efficiently transferring a multidrug resistance phenotype to cells without requiring drug selection. This approach will fac...
Sábháilte in:
| Foilsithe in: | Proc Natl Acad Sci U S A |
|---|---|
| Príomhchruthaitheoirí: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
National Academy of Sciences
1988
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1595 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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