Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria.
Mutagenic specificity of 2-acetylaminofluorene (AAF) has been established in mammalian cells and several strains of bacteria by using a shuttle plasmid vector containing a single N-(deoxyguanosin-8-yl)acetylaminofluorene (C8-dG-AAF) adduct. The nucleotide sequence of the gene conferring tetracycline...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3278320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1586 |
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