Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria.

Mutagenic specificity of 2-acetylaminofluorene (AAF) has been established in mammalian cells and several strains of bacteria by using a shuttle plasmid vector containing a single N-(deoxyguanosin-8-yl)acetylaminofluorene (C8-dG-AAF) adduct. The nucleotide sequence of the gene conferring tetracycline...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Moriya, M, Takeshita, M, Johnson, F, Peden, K, Will, S, Grollman, A P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3278320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1586
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