A Complex Role for FGF-2 in Self-Renewal, Survival, and Adhesion of Human Embryonic Stem Cells

The transcription program that is responsible for the pluripotency of human ESCs (hESCs) is believed to be comaintained by exogenous fibroblast growth factor-2 (FGF-2), which activates FGF receptors (FGFRs) and stimulates the mitogen-activated protein kinase (MAPK) pathway. However, the same pathway...

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Detalhes bibliográficos
Main Authors: Eiselleova, Livia, Matulka, Kamil, Kriz, Vitezslav, Kunova, Michaela, Schmidtova, Zuzana, Neradil, Jakub, Tichy, Boris, Dvorakova, Dana, Pospisilova, Sarka, Hampl, Ales, Dvorak, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798073/
https://ncbi.nlm.nih.gov/pubmed/19544431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.128
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