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Enhanced memory responses to H1N1 influenza vaccination in the skin using vaccine coated-microneedles

BACKGROUND: Morbidity and mortality due to influenza could be reduced by improved vaccination. METHODS: To develop a novel skin delivery method for simple and self administration, we prepared microneedle patches with stabilized influenza vaccine and investigated their protective immune responses. RE...

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Main Authors: Kim, Yeu-Chun, Quan, Fu-Shi, Yoo, Dae-Goon, Compans, Richard W., Kang, Sang-Moo, Prausnitz, Mark R.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798016/
https://ncbi.nlm.nih.gov/pubmed/20017632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/649228
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